Description

4-Chloro-3-Pyrrolidin-1-Yl-Benzoic Acid is a high-value benzoic acid derivative featuring a pyrrolidine substituent, serving as a critical synthetic intermediate in advanced organic chemistry. This compound is essential for research and development in the pharmaceutical sector, where it is used to construct novel molecular scaffolds with potential biological activity. It is primarily sought after by fine chemical manufacturers and R&D laboratories engaged in medicinal chemistry and agrochemical synthesis.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its unique pyrrolidine-chlorophenyl pharmacophore.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up production under cGMP conditions for clinical trial materials.

Basic Information

Product Name	4-Chloro-3-Pyrrolidin-1-Yl-Benzoic Acid
CAS No.	107946-68-9
Molecular Formula	C11H12ClNO2
Molecular Weight	225.67 g/mol
Synonyms	4-Chloro-3-(1-pyrrolidinyl)benzoic acid; 3-(Pyrrolidin-1-yl)-4-chlorobenzoic acid; Benzoic acid, 4-chloro-3-(1-pyrrolidinyl)-; 4-Chloro-3-pyrrolidin-1-ylbenzoic acid; 4-Chloro-3-(pyrrolidin-1-yl)benzoic acid; 107946-68-9; 4-Chloro-3-pyrrolidinylbenzoic acid
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Pyrrolidin-1-Yl-Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.