Description

3-Quinolinecarboxylic Acid, 1-Cyclopropyl-5,6,7,8-Tetrafluoro-1,4-Dihydro-4-Oxo-, Ethyl Ester is a high-purity, fluorinated quinolone derivative building block of significant interest in advanced organic synthesis. This compound matters as a critical intermediate for developing novel active pharmaceutical ingredients (APIs), particularly within the fluoroquinolone antibiotic class, due to its unique cyclopropyl and tetrafluoro-substituted quinoline core. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the development of next-generation antibacterial agents and other specialized fluorinated heterocycles.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the research and production of advanced fluoroquinolone antibiotics.
• Organic Synthesis Building Block: Used in constructing complex fluorinated heterocyclic compounds for medicinal chemistry and material science.
• Antibacterial Agent Research: Serves as a core scaffold for structure-activity relationship (SAR) studies aimed at discovering new antibacterial drugs.
• Chemical Reference Standard: Utilized as a high-purity analytical standard in quality control and regulatory testing for pharmaceutical manufacturing.
• Academic & Industrial R&D: Employed in research programs focused on fluorochemistry and the development of novel bioactive molecules.

Basic Information

Item	Detail
Product Name	3-Quinolinecarboxylic Acid, 1-Cyclopropyl-5,6,7,8-Tetrafluoro-1,4-Dihydro-4-Oxo-, Ethyl Ester
CAS No.	107564-02-3
Molecular Formula	C15H11F4NO3
Molecular Weight	329.25 g/mol
Synonyms	1-Cyclopropyl-5,6,7,8-tetrafluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid ethyl ester; Ethyl 1-cyclopropyl-5,6,7,8-tetrafluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate; 1-Cyclopropyl-5,6,7,8-tetrafluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid Ethyl Ester; 5,6,7,8-Tetrafluoro-1-cyclopropyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester; Fluoroquinolone Intermediate Ester; CP-99,219 Ethyl Ester Derivative
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid, 1-Cyclopropyl-5,6,7,8-Tetrafluoro-1,4-Dihydro-4-Oxo-, Ethyl Ester is manufactured under strict quality management systems. The product undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation, suitable for demanding research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical methods is provided with each batch to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.