Description

4-(3-Chloro-2-Fluorophenyl)Benzoic Acid is a high-purity, multi-functional aromatic carboxylic acid derivative, serving as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis. Its core value lies in enabling the development of novel active compounds, particularly in life sciences research and fine chemical manufacturing. This product is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for complex synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and fungicides, leveraging its halogenated aromatic structure.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing complex organic molecules used in electronic displays and optoelectronic devices.
• Polymer Modification: Acts as a monomer or functionalizing agent to introduce specific aromatic and carboxylic acid groups into polymer chains, enhancing material properties.
• Organic Synthesis Building Block: Utilized in Suzuki-Miyaura and other cross-coupling reactions to construct complex biaryl structures prevalent in medicinal chemistry.
• Research & Development: A valuable compound for academic and industrial research in developing new synthetic methodologies and exploring structure-activity relationships (SAR).

Basic Information

Product Name	4-(3-Chloro-2-Fluorophenyl)Benzoic Acid
CAS No.	107517-13-5
Molecular Formula	C13H8ClFO2
Molecular Weight	250.65 g/mol
Synonyms	[4-(3-Chloro-2-fluorophenyl)phenyl]formic acid; Benzoic acid, 4-(3-chloro-2-fluorophenyl)-; 3-Chloro-2-fluoro-4'-carboxybiphenyl; 4'-Carboxy-3'-chloro-2'-fluorobiphenyl; 2-Fluoro-3-chloro-4-biphenylcarboxylic acid; Biphenyl-4-carboxylic acid, 3-chloro-2-fluoro-; 4-Biphenylcarboxylic acid, 3-chloro-2-fluoro-
EINECS	Contact for details

Quality Control

Our 4-(3-Chloro-2-Fluorophenyl)Benzoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis and development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.