Description

(2S,3S)-trans-2-Methyl-3-Phenyloxirane-2-Methanol is a high-purity chiral epoxide derivative, a critical building block in asymmetric synthesis. Its defined stereochemistry and functional group versatility make it an essential intermediate for creating enantiomerically pure compounds. This product is primarily needed by research and development laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of active pharmaceutical ingredients (APIs), chiral ligands, and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the asymmetric synthesis of active pharmaceutical ingredients (APIs), particularly in cardiovascular and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators where specific stereochemistry is crucial for bioactivity.
• Chiral Ligand & Catalyst Preparation: Serves as a precursor for synthesizing sophisticated chiral ligands and organocatalysts used in enantioselective transformations.
• Fine Chemical Manufacturing: Employed in the multistep synthesis of complex fragrance compounds, flavors, and advanced material precursors.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry, exploring new asymmetric epoxidation and ring-opening reactions.

Basic Information

Product Name	(2S,3S)-trans-2-Methyl-3-Phenyloxirane-2-Methanol
CAS No.	107033-44-3
Molecular Formula	C11H14O2
Molecular Weight	178.23 g/mol
Synonyms	(2S,3S)-2-(Hydroxymethyl)-2-methyl-3-phenyloxirane; (2S,3S)-trans-2-Methyl-3-phenylglycidol; (2S,3S)-Phenylglycidol, 2-methyl-; trans-(2S,3S)-2-Methyl-3-phenyloxiranemethanol; (2S,3S)-2-Methyl-3-phenyloxirane-2-methanol; (2S,3S)-2-Methyl-3-phenyl-2,3-epoxy-1-propanol; Chiral Phenylglycidol derivative
EINECS	Contact for details

Quality Control

Our (2S,3S)-trans-2-Methyl-3-Phenyloxirane-2-Methanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure high enantiomeric excess (ee) and chemical purity. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee consistency and traceability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.