Description

8-Methyl-2-Pyridin-4-Ylquinoline-4-Carboxylic Acid is a high-purity, synthetically valuable heterocyclic carboxylic acid building block. This compound matters as a critical intermediate in the research and development of advanced pharmaceutical agents, particularly in medicinal chemistry programs targeting complex biological pathways. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for synthesizing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in kinase inhibitor research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Agrochemical Development: Intermediate in the creation of new generation herbicides or fungicides with specific modes of action.
• Ligand Synthesis: Serves as a precursor for chelating ligands in catalysis or metal-organic frameworks (MOFs).
• Fine Chemical Synthesis: Employed in multi-step synthetic routes to produce complex, high-value specialty chemicals.
• Academic & Institutional Research: Used in universities and research institutes for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	8-Methyl-2-Pyridin-4-Ylquinoline-4-Carboxylic Acid
CAS No.	107027-42-9
Molecular Formula	C₁₇H₁₂N₂O₂
Molecular Weight	276.29 g/mol
Synonyms	8-Methyl-2-(pyridin-4-yl)quinoline-4-carboxylic acid; 2-(4-Pyridinyl)-8-methyl-4-quinolinecarboxylic acid; 4-Quinolinecarboxylic acid, 8-methyl-2-(4-pyridinyl)-; 8-Methyl-2-(4-pyridyl)quinoline-4-carboxylic acid; 107027-42-9; 8-Methyl-2-(4-pyridinyl)-4-quinolinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 8-Methyl-2-Pyridin-4-Ylquinoline-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.