Description

Ethyl (3R)-4-Benzylmorpholine-3-Carboxylate is a high-purity chiral building block and pharmaceutical intermediate of significant synthetic value. This compound is crucial for the development of enantiomerically pure active pharmaceutical ingredients (APIs) and fine chemicals, where stereochemical control is paramount. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors for process development and scale-up.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug molecules, particularly those targeting neurological and cardiovascular pathways.
• Asymmetric Synthesis: Serves as a versatile precursor for constructing morpholine-based scaffolds with defined stereochemistry in medicinal chemistry.
• Agrochemical Research: Used in the development of novel, enantioselective pesticides and herbicides.
• Ligand and Catalyst Development: Employed as a starting material for creating chiral ligands used in transition metal catalysis.
• Academic & Contract Research: A valuable reagent for methodological studies in organic and process chemistry within R&D laboratories.
• Fine Chemical Production: Integral to the multi-step synthesis of specialty chemicals requiring high optical purity.

Basic Information

Product Name	Ethyl (3R)-4-Benzylmorpholine-3-Carboxylate
CAS No.	106910-85-4
Molecular Formula	C14H19NO3
Molecular Weight	249.31 g/mol
Synonyms	(R)-Ethyl 4-benzylmorpholine-3-carboxylate; (3R)-4-Benzylmorpholine-3-carboxylic acid ethyl ester; Ethyl (R)-4-benzylmorpholine-3-carboxylate; 4-Benzyl-3-morpholinecarboxylic acid ethyl ester, (3R)-; UNII-1F9K3H8F1K; 1F9K3H8F1K; (R)-4-Benzylmorpholine-3-carboxylic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl (3R)-4-Benzylmorpholine-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.