Description

3,5-Ditrifluoromethyl-Benzyl-Hydrazine is a high-value, multi-functional aromatic hydrazine derivative characterized by its two electron-withdrawing trifluoromethyl groups. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry, enabling the introduction of the benzyl-hydrazine moiety into complex molecular architectures. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of heterocyclic compounds, hydrazide-based drugs, and potential enzyme inhibitors.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and plant growth regulators leveraging the CF3 groups for enhanced bioactivity and metabolic stability.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Intermediate for synthesizing fluorinated polymers and advanced organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Sourced by CROs and CDMOs for client-specific research projects and scale-up campaigns.
• Academic Research: Employed in university and institutional labs for methodological studies in organic synthesis and fluorine chemistry.

Basic Information

Product Name	3,5-Ditrifluoromethyl-Benzyl-Hydrazine
CAS No.	106898-35-5
Molecular Formula	C9H8F6N2
Molecular Weight	258.17 g/mol
Synonyms	1-(3,5-Bis(trifluoromethyl)benzyl)hydrazine; (3,5-Bis(trifluoromethyl)phenyl)methanamine, N-amino-; 3,5-Bis(trifluoromethyl)benzylhydrazine; α-Hydrazino-3,5-bis(trifluoromethyl)toluene; Hydrazine, [(3,5-bis(trifluoromethyl)phenyl)methyl]-; 3,5-Ditrifluoromethylbenzyl Hydrazine; 1-(3,5-Ditrifluoromethylbenzyl)hydrazine
EINECS	Contact for details

Quality Control

Our production of 3,5-Ditrifluoromethyl-Benzyl-Hydrazine adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data including HPLC purity, NMR confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is supplied with each batch, documenting compliance with agreed specifications. Our quality system supports development under cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation. Keep away from strong oxidizers and acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.