Description

4-(tert-Butyldimethylsilyloxy)Indole is a key protected indole derivative, widely utilized as a versatile synthetic intermediate in advanced organic chemistry. Its primary value lies in the tert-butyldimethylsilyl (TBDMS) protecting group, which effectively shields the hydroxyl functionality during multi-step synthesis, enabling selective reactions elsewhere on the indole core. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly for the development of complex molecules, active pharmaceutical ingredients (APIs), and novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing indole-based drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of novel pesticides and herbicides that incorporate the indole scaffold.
• Organic Synthesis Reagent: Serves as a protected precursor for the preparation of more complex indole derivatives and natural product analogs.
• Material Science Research: Employed in the development of organic semiconductors and advanced functional materials with specific electronic properties.
• Academic & R&D Laboratories: A valuable tool for methodological development and exploring new synthetic pathways in heterocyclic chemistry.

Basic Information

Item	Detail
Product Name	4-(tert-Butyldimethylsilyloxy)Indole
CAS No.	106792-40-9
Molecular Formula	C14H21NOSi
Molecular Weight	247.41 g/mol
Synonyms	4-[(tert-Butyldimethylsilyl)oxy]-1H-indole; 4-TBDMS-Oxyindole; 4-Hydroxyindole TBDMS ether; 4-(tert-Butyldimethylsiloxy)indole; 4-(TBDMSO)Indole; 4-Indolol, TBDMS derivative; 1H-Indol-4-ol, 1-(1,1-dimethylethyl)dimethylsilyl ether
EINECS	Contact for details

Quality Control

Our 4-(tert-Butyldimethylsilyloxy)Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and may benefit from storage under an inert atmosphere or with desiccant for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.