Description

(R)-α-(Cbz-Amino)-9-Anthracenepropanoic Acid is a chiral, non-natural amino acid derivative featuring a bulky anthracene fluorophore and a carboxybenzyl (Cbz) protecting group. This compound is a critical building block in advanced organic synthesis, particularly for the development of novel pharmaceuticals and bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in peptide mimetics, chiral catalyst design, and fluorescence-based probe development.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used to incorporate a rigid, fluorescent anthracene moiety into peptide chains to study structure-activity relationships (SAR) and conformational stability.
• Asymmetric Synthesis: Serves as a chiral auxiliary or precursor for ligands in catalytic asymmetric transformations.
• Fluorescent Probe Development: The anthracene group makes it suitable for creating molecular probes and sensors for biochemical and diagnostic applications.
• Academic & Industrial Research: Employed in medicinal chemistry programs for lead optimization and in material science for novel chiral materials.

Basic Information

Product Name	(R)-α-(Cbz-Amino)-9-Anthracenepropanoic Acid
CAS No.	106749-30-8
Molecular Formula	C25H21NO4
Molecular Weight	399.44 g/mol
Synonyms	(R)-2-(((Benzyloxy)carbonyl)amino)-3-(anthracen-9-yl)propanoic acid; (R)-N-Cbz-9-Anthrylalanine; (R)-α-[(Benzyloxycarbonyl)amino]-9-anthracenepropanoic Acid; (R)-N-Carbobenzoxy-9-anthrylalanine; (R)-Cbz-9-Anth-Ala-OH; (R)-2-((((Benzyloxy)carbonyl)amino)-3-(9-anthryl)propionic acid; (R)-N-Z-9-Anthrylalanine
EINECS	Contact for details

Quality Control

Our (R)-α-(Cbz-Amino)-9-Anthracenepropanoic Acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.