Description

Diacetato[(S)-(-)-2,2'-Bis(Di-p-Tolylphosphino)-1,1'-Binaphthyl]Ruthenium(II) is a high-value, chiral ruthenium complex widely recognized as a highly efficient asymmetric hydrogenation catalyst. This compound is critical for achieving high enantioselectivity and yield in the synthesis of optically active intermediates. It is primarily needed by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and fine chemical industries for the manufacture of chiral active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of functionalized olefins, ketones, and imines in pharmaceutical synthesis.
• Pharmaceutical Intermediate Production: Key for manufacturing chiral building blocks for APIs, including β-amino acids, lactams, and alcohols.
• Fine Chemical Synthesis: Enables the production of high-value, optically pure flavors, fragrances, and agrochemical intermediates.
• Academic and Industrial R&D: Serves as a benchmark catalyst in method development and process chemistry research for new asymmetric transformations.
• Process Scale-Up: Suitable for transitioning from laboratory-scale discovery to pilot and commercial-scale manufacturing due to its robustness and high turnover number.

Basic Information

Product Name	Diacetato[(S)-(-)-2,2'-Bis(Di-p-Tolylphosphino)-1,1'-Binaphthyl]Ruthenium(II)
CAS No.	106681-15-6
Molecular Formula	C60H52O4P2Ru
Molecular Weight	990.07 g/mol
Synonyms	(S)-Ru(OAc)2(Tol-BINAP); (S)-(-)-2,2'-Bis(di-p-tolylphosphino)-1,1'-binaphthyl ruthenium(II) diacetate; Ru(OAc)2[(S)-Tol-BINAP]; (S)-Tol-BINAP Ru(II) diacetate; Ruthenium(II) (S)-Tol-BINAP diacetate; (S)-TolBINAP-Ru(OAc)2; Asymmetric hydrogenation catalyst Ru-Tol-BINAP; [Ru((S)-Tol-BINAP)(OAc)2]
EINECS	Contact for details

Quality Control

Our Diacetato[(S)-(-)-2,2'-Bis(Di-p-Tolylphosphino)-1,1'-Binaphthyl]Ruthenium(II) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high catalytic performance. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, chiral integrity, and metal content. We adhere to cGMP standards where applicable, ensuring material suitability for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to maintain stability and prevent oxidation. The container should be kept in a cool, dry, and well-ventilated area, separate from incompatible materials.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Ruthenium Content	10.0 - 10.5%
Solubility	Soluble in dichloromethane, toluene; slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.