Description

n-Hydroxy-4-(1-Naphthalenyl)-Benzamide is a specialized organic compound featuring a hydroxamic acid functional group linked to a naphthalene-benzene core. This unique structure makes it a valuable intermediate and research chemical for the development of novel pharmaceutical agents and biochemical tools. It is primarily sought after by research institutions and fine chemical manufacturers engaged in medicinal chemistry, particularly for the synthesis of enzyme inhibitors and metalloproteinase modulators.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential therapeutic agents, especially hydroxamate-based drugs.
• Biochemical Research: Used as a reference standard or precursor in studies involving enzyme inhibition, particularly for metalloenzymes like matrix metalloproteinases (MMPs) and histone deacetylases (HDACs).
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize drug candidate potency and selectivity.
• Organic Synthesis: Employed in advanced organic reactions to introduce the hydroxamic acid pharmacophore into complex molecules.
• Agrochemical Research: Potential intermediate for developing novel crop protection agents with chelating or enzyme-inhibiting properties.

Basic Information

Product Name	n-Hydroxy-4-(1-Naphthalenyl)-Benzamide
CAS No.	106359-61-9
Molecular Formula	C₁₇H₁₃NO₂
Molecular Weight	263.29 g/mol
Synonyms	4-(Naphthalen-1-yl)benzohydroxamic acid; N-Hydroxy-4-(1-naphthyl)benzamide; 4-(1-Naphthyl)benzhydroxamic acid; 1-Naphthalenyl-Benzamide, N-hydroxy-4-; Benzamide, N-hydroxy-4-(1-naphthalenyl)-; 106359-61-9; 4-(1-Naphthyl)-N-hydroxybenzamide
EINECS	Contact for details

Quality Control

Our n-Hydroxy-4-(1-Naphthalenyl)-Benzamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.