Description

1-(2-Fluoro-Benzyl)-1H-[1,2,3]Triazole-4-Carboxylic Acid is a high-purity fluorinated triazole derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular architecture, which combines a reactive carboxylic acid group with a fluorinated benzyl-triazole core, enabling precise modifications for developing novel compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for creating active ingredients and fine chemicals where fluorine substitution is desired for enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the fluorinated triazole moiety contributes to efficacy.
• Material Science Research: Employed in the synthesis of specialty polymers, ligands for catalysis, and functional materials.
• Chemical Biology Probes: Serves as a versatile scaffold for creating fluorescent tags, enzyme inhibitors, and other molecular probes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke chemical synthesis projects.

Basic Information

Product Name	1-(2-Fluoro-Benzyl)-1H-[1,2,3]Triazole-4-Carboxylic Acid
CAS No.	106308-42-3
Molecular Formula	C10H8FN3O2
Molecular Weight	221.19 g/mol
Synonyms	1-[(2-Fluorophenyl)methyl]-1H-1,2,3-triazole-4-carboxylic acid; 1-(2-Fluorobenzyl)-1H-1,2,3-triazole-4-carboxylic acid; 1H-1,2,3-Triazole-4-carboxylic acid, 1-[(2-fluorophenyl)methyl]-; 2-Fluoro-α-(4-carboxy-1H-1,2,3-triazol-1-ylmethyl)benzene; 106308-42-3; FBTCA
EINECS	Contact for details

Quality Control

Our 1-(2-Fluoro-Benzyl)-1H-[1,2,3]Triazole-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP and ISO guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under dry, inert conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.