Description

n-Tosyl-3-Pyrrolecarboxylic Acid is a versatile and synthetically valuable pyrrole derivative, characterized by the presence of both a tosyl protecting group and a carboxylic acid functionality. This compound serves as a crucial high-purity building block in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily required by pharmaceutical R&D and fine chemical sectors for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Building block for developing advanced active ingredients with specific biological activity.
• Material Science Research: Used in the development of organic semiconductors, conductive polymers, and advanced organic frameworks (MOFs/COFs).
• Academic & Industrial R&D: Essential reagent for methodological studies in heterocyclic and peptide chemistry.
• Dye & Pigment Industry: Intermediate for synthesizing specialized pyrrole-based colorants and functional dyes.
• Chemical Biology: Useful for creating probes and labeled compounds for biochemical research.

Basic Information

Product Name	n-Tosyl-3-Pyrrolecarboxylic Acid
CAS No.	106058-86-0
Molecular Formula	C12H11NO4S
Molecular Weight	265.29 g/mol
Synonyms	1-Tosyl-1H-pyrrole-3-carboxylic acid; 3-Carboxy-1-(p-toluenesulfonyl)pyrrole; 1H-Pyrrole-3-carboxylic acid, 1-[(4-methylphenyl)sulfonyl]-; N-Tosylpyrrole-3-carboxylic Acid; 1-Tosyl-3-carboxypyrrole; 1-(Tosyl)-3-pyrrolecarboxylic Acid; 1-(4-Methylbenzenesulfonyl)-1H-pyrrole-3-carboxylic acid; N-(p-Toluenesulfonyl)-3-pyrrolecarboxylic Acid
EINECS	Contact for details

Quality Control

Our n-Tosyl-3-Pyrrolecarboxylic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific project requirements. We adhere to cGMP principles for production intended for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.