Description

1,4-Dioxaspiro[4.4]Nonane,2,3,7-Trimethyl-,[2R-[2-α-,3-Bta-,5-α-(R*)]]-(9Ci) is a high-purity, stereochemically defined spirocyclic compound with the CAS number 106034-27-9. This specialized intermediate is valued for its unique structural framework, which is critical for synthesizing complex molecules in advanced research and development. It is primarily sought after by pharmaceutical and fine chemical manufacturers for applications in asymmetric synthesis and the development of novel active ingredients.

Application

This chiral spirocyclic dioxolane serves as a versatile building block in sophisticated organic synthesis. Key application areas include:

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Employed as a stereocontrolling agent or chiral auxiliary in reactions requiring high enantioselectivity.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, including fragrances, flavors, and advanced materials.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploring new chemical spaces in research laboratories.
• Agrochemical Synthesis: Potential intermediate in the development of novel, stereospecific pesticides and herbicides.

Basic Information

Item	Details
Product Name	1,4-Dioxaspiro[4.4]Nonane,2,3,7-Trimethyl-,[2R-[2-α-,3-Bta-,5-α-(R*)]]-(9Ci)
CAS No.	106034-27-9
Molecular Formula	C10H18O2
Molecular Weight	170.25 g/mol
Synonyms	(2R,3S,5R)-2,3,7-Trimethyl-1,4-dioxaspiro[4.4]nonane; (2R,3S,5R)-2,3,7-Trimethyl-1,4-dioxaspiro[4.4]nonane; Trimethyl-dioxaspiro[4.4]nonane (stereoisomer); Spirocyclic dioxolane derivative; Chiral spiroketal; 1,4-Dioxaspiro[4.4]nonane, 2,3,7-trimethyl-, (2R,3S,5R)-; 106034-27-9; (2R,3S,5R)-2,3,7-Trimethyl-1,4-dioxaspiro[4.4]nonane
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Quality is verified through advanced analytical techniques including chiral HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.