Description

α-Hydroxy-6-Methoxy-α-Methyl-2-Naphthaleneacetic Acid Methyl Ester is a high-purity, synthetically derived naphthalene derivative ester, serving as a critical advanced intermediate in pharmaceutical synthesis. Its value lies in its precise molecular structure, which is essential for constructing complex active pharmaceutical ingredients (APIs) with specific stereochemistry and functional groups. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries engaged in the development and production of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of proprietary drug candidates and active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new bioactive molecules.
• Fine Chemical Synthesis: Employed in the production of complex, high-value specialty chemicals requiring specific naphthalene-based frameworks.
• Process Chemistry: Serves as a standardized intermediate in scale-up and optimization of synthetic routes for commercial manufacturing.

Basic Information

Product Name	α-Hydroxy-6-Methoxy-α-Methyl-2-Naphthaleneacetic Acid Methyl Ester
CAS No.	105937-62-0
Molecular Formula	C₁₅H₁₆O₄
Molecular Weight	260.29 g/mol
Synonyms	6-Methoxy-α-methyl-2-naphthaleneacetic acid, methyl ester, α-hydroxy-; Methyl 2-(6-methoxy-2-naphthyl)propanoate, α-hydroxy-; (RS)-Methyl 2-hydroxy-2-(6-methoxy-2-naphthyl)propanoate; α-Hydroxy-6-methoxy-α-methyl-2-naphaleneacetic acid methyl ester; 2-Naphthaleneacetic acid, α-hydroxy-6-methoxy-α-methyl-, methyl ester; Methyl α-hydroxy-6-methoxy-α-methyl-2-naphthaleneacetate
EINECS	Contact for details

Quality Control

Our α-Hydroxy-6-Methoxy-α-Methyl-2-Naphthaleneacetic Acid Methyl Ester is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.