Description

3,3,3-Trifluoro-1-(Phenylsulfonyl)-1-Pro Pene is a high-value organofluorine building block featuring a reactive terminal alkene and a phenylsulfonyl group. This compound is essential for advanced organic synthesis, particularly in the construction of complex molecules through cross-coupling and nucleophilic addition reactions. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical and agrochemical industries for creating novel fluorinated active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, including kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Used in the research and production of novel fluorinated pesticides and herbicides, where fluorine atoms enhance biological activity and stability.
• Material Science Research: Serves as a monomer or precursor for specialty polymers and advanced materials with unique surface properties.
• Cross-Coupling Reactions: Acts as an effective coupling partner in Heck, Suzuki, and other palladium-catalyzed reactions to introduce the trifluoromethyl and phenylsulfonyl motifs.
• Nucleophilic Addition Substrate: The electron-deficient alkene is receptive to additions from various nucleophiles, enabling diverse molecular diversification.
• Ligand and Catalyst Development: Utilized in the synthesis of novel chiral ligands or organocatalysts for asymmetric synthesis.

Basic Information

Product Name	3,3,3-Trifluoro-1-(Phenylsulfonyl)-1-Pro Pene
CAS No.	105924-64-9
Molecular Formula	C9H7F3O2S
Molecular Weight	236.21 g/mol
Synonyms	1-(Phenylsulfonyl)-3,3,3-trifluoropropene; 3,3,3-Trifluoro-1-(phenylsulfonyl)prop-1-ene; (Phenylsulfonyl)trifluoropropene; 3,3,3-Trifluoro-1-(benzenesulfonyl)-1-propene; 1-(Benzenesulfonyl)-3,3,3-trifluoropropene; 3,3,3-Trifluoro-1-(phenylsulfonyl)propene; Trifluoromethyl vinyl phenyl sulfone
EINECS	Contact for details

Quality Control

Our 3,3,3-Trifluoro-1-(Phenylsulfonyl)-1-Pro Pene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.