Description

1,3-Dioxolane, 2-Methyl-4-[(2-Propynyloxy)Methyl]- (9Ci) is a specialized heterocyclic compound featuring a dioxolane ring functionalized with a propargyl ether group. This unique molecular structure makes it a valuable versatile building block and reactive intermediate in advanced organic synthesis. It is primarily sought after by pharmaceutical, agrochemical, and fine chemical research and development teams for constructing complex molecules.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of active pharmaceutical ingredients (APIs), particularly for molecules requiring cyclic acetal or propargyl ether functionalities.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators where its reactive groups enable specific molecular modifications.
• Fine Chemical Production: Acts as a precursor for specialty chemicals, including flavors, fragrances, and advanced polymer additives.
• Cross-Coupling Reactions: The propargyloxy group can participate in click chemistry (e.g., copper-catalyzed azide-alkyne cycloaddition) for bioconjugation and material science applications.
• Ligand and Catalyst Development: Utilized in the synthesis of novel chelating ligands or organocatalysts for asymmetric synthesis.
• Academic and Industrial R&D: A valuable reagent for methodological studies in organic chemistry and the exploration of new synthetic pathways.

Basic Information

Product Name	1,3-Dioxolane, 2-Methyl-4-[(2-Propynyloxy)Methyl]- (9Ci)
CAS No.	105922-60-9
Molecular Formula	C8H12O3
Molecular Weight	156.18 g/mol
Synonyms	2-Methyl-4-(prop-2-yn-1-yloxymethyl)-1,3-dioxolane; 4-[(2-Propynyloxy)methyl]-2-methyl-1,3-dioxolane; 2-Methyl-4-(propargyloxymethyl)-1,3-dioxolane; Propargyloxymethyl methyl dioxolane; Methyl propargyl ether of hydroxymethyl methyl dioxolane
EINECS	Contact for details

Quality Control

Our high-purity 1,3-Dioxolane derivative is manufactured under strict quality control protocols. Every batch is analyzed using advanced techniques like GC, HPLC, and NMR to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality system is designed to meet the stringent requirements of GMP and ISO standards for research and industrial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Recommended storage temperature is 2-8°C for long-term stability. Keep away from heat, sparks, open flames, and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 3.0%
Specific Gravity (20°C)	1.05 - 1.10
Refractive Index (20°C)	1.430 - 1.440

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.