Description

5-Chloro-2,4,8-Trimethylquinoline is a halogenated quinoline derivative that serves as a versatile and critical synthetic intermediate in advanced organic chemistry. Its unique substitution pattern makes it a valuable building block for constructing complex molecular architectures with tailored properties. This compound is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for antimalarial, antibacterial, and anticancer research.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides due to its bioactive quinoline core.
• Material Science Research: Serves as a monomer or ligand for creating organic semiconductors, luminescent materials, and metal-organic frameworks (MOFs).
• Dye and Pigment Industry: Acts as a foundational structure for synthesizing specialized quinoline-based dyes and colorants.
• Catalyst Ligand Preparation: Utilized to synthesize complex ligands for transition metal catalysis in fine chemical production.
• Academic & Contract Research: Essential reagent for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	5-Chloro-2,4,8-Trimethylquinoline
CAS No.	105908-43-8
Molecular Formula	C₁₂H₁₂ClN
Molecular Weight	205.68 g/mol
Synonyms	5-Chloro-2,4,8-trimethylquinoline; 2,4,8-Trimethyl-5-chloroquinoline; Quinoline, 5-chloro-2,4,8-trimethyl-; 105908-43-8
EINECS	Contact for details

Quality Control

Our 5-Chloro-2,4,8-Trimethylquinoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is supplied with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.