Description

n-Boc-o-Tosyl Hydroxylamine is a versatile and highly valuable protected hydroxylamine derivative, primarily used as a key building block in organic synthesis. Its core value proposition lies in providing a stable, reactive handle for the controlled introduction of the N-O functional group, which is crucial for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for the synthesis of oximes, hydroxamic acids, and other nitrogen-oxygen containing target molecules.

Application

• Pharmaceutical Intermediate: A critical reagent in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing hydroxamic acid or oxime moieties.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require specific N-O linkage chemistry.
• Peptide & Protein Modification: Employed for the site-specific modification of peptides and proteins, enabling the study of protein function or the creation of bioconjugates.
• Polymer Chemistry: Serves as a functional monomer or cross-linking agent in the production of specialty polymers with tailored properties.
• Material Science Research: Utilized in the development of novel organic frameworks and functionalized surfaces.
• Academic & R&D Laboratories: A fundamental tool for methodological development in organic synthesis and catalysis studies.

Basic Information

Product Name	n-Boc-o-Tosyl Hydroxylamine
CAS No.	105838-14-0
Molecular Formula	C₁₂H₁₇NO₅S
Molecular Weight	287.33 g/mol
Synonyms	tert-Butyl N-[(4-methylphenyl)sulfonyl]oxycarbamate; N-(tert-Butoxycarbonyl)-O-(p-toluenesulfonyl)hydroxylamine; Boc-ONH-Ts; O-(p-Tolylsulfonyl)hydroxylamine tert-Butyl Carbamate; N-Boc-O-tosylhydroxylamine; tert-Butyl [(4-methylphenyl)sulfonyl]oxycarbamate; N-Boc-hydroxylamine-O-tosylate; 1,1-Dimethylethyl N-[[(4-methylphenyl)sulfonyl]oxy]carbamate
EINECS	Contact for details

Quality Control

Our n-Boc-o-Tosyl Hydroxylamine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality parameters. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from moisture and direct light exposure. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	95 - 100 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.