Description

Diexo-3-Amino-Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid Ethyl Ester is a specialized bicyclic amino acid derivative with a constrained, rigid molecular framework. This compound is a high-value chiral building block prized for its role in the synthesis of complex, biologically active molecules. It is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to create novel compounds with enhanced stereochemical control.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in antiviral, neurological, and anti-inflammatory drug discovery programs.
• Agrochemical Research: Used as a precursor in the development of new pesticides and herbicides, leveraging its unique bicyclic structure for target specificity.
• Peptidomimetics & Conformationally Restricted Peptides: Serves as a non-natural amino acid analog to introduce rigidity into peptide chains, improving metabolic stability and binding affinity.
• Asymmetric Synthesis Catalyst Ligand: The amino and ester functionalities make it a potential precursor for chiral ligands and organocatalysts used in enantioselective transformations.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific thermal or mechanical properties due to its strained ring system.
• Academic & Process Chemistry: Employed in methodological studies and scale-up process development for complex organic syntheses.

Basic Information

Product Name	Diexo-3-Amino-Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid Ethyl Ester
CAS No.	105786-36-5
Molecular Formula	C10H15NO2
Molecular Weight	181.23 g/mol
Synonyms	(1R,2S,3R,4S)-3-Aminobicyclo[2.2.1]hept-5-ene-2-carboxylic acid ethyl ester; Ethyl (1R,2S,3R,4S)-3-aminobicyclo[2.2.1]hept-5-ene-2-carboxylate; exo-3-Aminonorbornene-2-carboxylic acid ethyl ester; (1R,2S,3R,4S)-3-Amino-2-ethoxycarbonylbicyclo[2.2.1]hept-5-ene; Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid, 3-amino-, ethyl ester, (1R,2S,3R,4S)-; Ethyl 3-aminobicyclo[2.2.1]hept-5-ene-2-carboxylate
EINECS	Contact for details

Quality Control

Our Diexo-3-Amino-Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.