Description

2,4-Dichloro-6-Methoxyquinazoline is a high-purity, versatile heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its dual reactive chlorine sites, which allow for selective, sequential functionalization to create complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, serving as a key precursor for the development of novel active ingredients and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of kinase inhibitors, anticancer agents, and other biologically active quinazoline derivatives.
• Agrochemical Synthesis: Used in the research and development of new herbicides and fungicides that leverage the quinazoline scaffold.
• Material Science Research: Serves as a building block for creating organic electronic materials, ligands for metal-organic frameworks (MOFs), and specialty polymers.
• Chemical Biology & Proteomics: Employed in the design and synthesis of chemical probes and affinity tags for target identification and validation studies.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring regioselective modification of the quinazoline core.

Basic Information

Product Name	2,4-Dichloro-6-Methoxyquinazoline
CAS No.	105763-77-7
Molecular Formula	C9H6Cl2N2O
Molecular Weight	229.06 g/mol
Synonyms	6-Methoxy-2,4-dichloroquinazoline; 2,4-Dichloro-6-methoxy-quinazoline; Quinazoline, 2,4-dichloro-6-methoxy-; 2,4-Dichloro-6-methoxy-1,3-diazanaphthalene
EINECS	Contact for details

Quality Control

Our 2,4-Dichloro-6-Methoxyquinazoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.