Description

(R)-2-Aminobut-3-Enoic Acid Hydrochloride is a high-purity chiral building block and amino acid derivative essential for advanced organic synthesis. Its primary value lies in serving as a key intermediate for the preparation of novel pharmaceuticals, particularly in the development of enzyme inhibitors and other bioactive molecules. This compound is critically needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of complex, stereochemically defined active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of new drug candidates, especially those targeting neurological and metabolic disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and the synthesis of compound libraries for high-throughput screening.
• Peptidomimetics Synthesis: Serves as a constrained, unsaturated amino acid analog for constructing novel peptide-like molecules with enhanced stability and bioavailability.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in catalytic asymmetric reactions to introduce chirality into complex molecular architectures.
• Bioconjugation & Probe Development: Useful for creating labeled compounds or conjugates for biochemical and diagnostic applications.
• Academic & Industrial R&D: Fundamental building block in academic laboratories and corporate R&D departments for exploring new chemical entities and synthetic methodologies.

Basic Information

Product Name	(R)-2-Aminobut-3-Enoic Acid Hydrochloride
CAS No.	105763-41-5
Molecular Formula	C4H8ClNO2
Molecular Weight	137.56 g/mol
Synonyms	(R)-2-Amino-3-butenoic acid hydrochloride; (R)-2-Amino-but-3-enoic acid hydrochloride; (2R)-2-Aminobut-3-enoic acid hydrochloride; (R)-2-Amino-3-butenoic acid HCl; D-2-Aminobut-3-enoic acid hydrochloride; (R)-2-Amino-crotonic acid hydrochloride; (R)-3-Butenoic acid, 2-amino-, hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-2-Aminobut-3-Enoic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and decomposition. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.