Description

4-Iodo-3-Nitroaniline is a halogenated nitroaniline derivative that serves as a versatile and valuable synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both an iodine substituent and a nitro group on an aniline core, makes it a critical building block for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors for applications such as drug discovery, ligand synthesis, and the development of functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring halogenated aromatic scaffolds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and pesticides where the iodine atom facilitates further functionalization.
• Dye and Pigment Manufacturing: Serves as a starting material for the production of specialized azo dyes and colorants.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalytic systems.
• Material Science Research: Building block for organic semiconductors, non-linear optical (NLO) materials, and other advanced functional polymers.
• Cross-Coupling Reactions: The iodine moiety makes it a suitable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form biaryl structures.

Basic Information

Product Name	4-Iodo-3-Nitroaniline
CAS No.	105752-04-3
Molecular Formula	C6H5IN2O2
Molecular Weight	264.02 g/mol
Synonyms	3-Nitro-4-iodoaniline; 4-Iodo-3-nitrobenzenamine; 1-Amino-4-iodo-3-nitrobenzene; 4-Iodo-3-nitro-phenylamine; Benzenamine, 4-iodo-3-nitro-; 4-Iodo-3-nitroaniline (primary name)
EINECS	Contact for details

Quality Control

Our 4-Iodo-3-Nitroaniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. Standard quality parameters include assay (HPLC), identification (IR), and control of related substances. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.