Description

2,2-Difluorocycloprop-1-Ylamine Hydrochloride is a high-value, fluorinated building block essential for advanced organic synthesis. This compound is particularly significant for introducing the strained, difluorinated cyclopropylamine moiety into target molecules, a key structural motif in medicinal chemistry. It is primarily required by pharmaceutical R&D and fine chemical manufacturers for developing novel active pharmaceutical ingredients (APIs), agrochemicals, and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical synthon for the synthesis of protease inhibitors, kinase inhibitors, and other bioactive molecules.
• Agrochemical Research: Used in creating novel herbicides and pesticides with enhanced properties due to the fluorine atoms.
• Material Science: Serves as a precursor for specialty polymers and advanced materials requiring fluorinated components.
• Chemical Biology: Employed in the development of molecular probes and enzyme inhibitors for biochemical research.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs for client-specific molecule construction.

Basic Information

Product Name	2,2-Difluorocycloprop-1-Ylamine Hydrochloride
CAS No.	105614-25-3
Molecular Formula	C3H6ClF2N
Molecular Weight	129.54 g/mol
Synonyms	2,2-Difluorocyclopropanamine hydrochloride; 1-Amino-2,2-difluorocyclopropane hydrochloride; 2,2-Difluorocyclopropylamine HCl; 2,2-Difluoro-1-cyclopropanamine hydrochloride; (2,2-Difluorocyclopropyl)amine hydrochloride; 1-Cyclopropanamine, 2,2-difluoro-, hydrochloride; 105614-25-3; 2,2-Difluorocycloprop-1-ylamine HCl
EINECS	Contact for details

Quality Control

Our 2,2-Difluorocycloprop-1-Ylamine Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, impurity profile, and identity confirmation. Our quality system is designed to meet the stringent requirements of pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.