Description

1-Nitropyrene-4,5-Oxide is a high-purity, specialized nitroarene oxide compound used as a critical reference standard and research chemical. Its primary value lies in its role as a metabolite and model compound for studying the environmental fate, metabolic activation, and genotoxic potential of polycyclic aromatic hydrocarbons (PAHs). This product is essential for researchers and quality control laboratories in the fields of environmental toxicology, analytical chemistry, and pharmaceutical research, where precise and reliable standards are required for method development and validation.

Application

• Analytical Reference Standard: Primary use as a certified standard for the quantification and identification of nitrated PAH derivatives in complex matrices via HPLC, GC-MS, or LC-MS.
• Toxicological Research: Serves as a key metabolite in studies investigating the DNA adduct formation, mutagenicity, and carcinogenicity of parent compounds like 1-nitropyrene.
• Environmental Monitoring: Used in the calibration of analytical instruments for detecting and monitoring airborne particulate matter, diesel exhaust, and soil contaminants.
• Biochemical Studies: Employed in enzymatic studies to understand the metabolic pathways (e.g., cytochrome P450) involved in the activation of nitro-PAHs.
• Pharmaceutical Impurity Profiling: Acts as a potential impurity or degradation product reference in the analysis of related pharmaceutical compounds.
• Material Science Research: Investigated as a precursor or intermediate in the synthesis of specialized organic materials or dyes.

Basic Information

Product Name	1-Nitropyrene-4,5-Oxide
CAS No.	105596-42-7
Molecular Formula	C₁₆H₉NO₃
Molecular Weight	263.25 g/mol
Synonyms	1-Nitropyrene 4,5-oxide; 4,5-Epoxy-4,5-dihydro-1-nitropyrene; 1-Nitro-4,5-epoxy-4,5-dihydropyrene; 1-NP 4,5-oxide; Pyrene, 1-nitro-4,5-epoxy-4,5-dihydro-; 1-Nitropyrene-4,5-epoxide
EINECS	Contact for details

Quality Control

Every batch of 1-Nitropyrene-4,5-Oxide is manufactured and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing, including chromatographic purity analysis and spectroscopic identification, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation. Keep the container in a cool, dry, and well-ventilated place, away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.