Description

Tr-Peg3 CAS NO 105589-77-3 is a specialized tri-functional polyethylene glycol (PEG) derivative, serving as a versatile linker and spacer molecule in advanced chemical synthesis. Its core value lies in providing a hydrophilic, flexible, and biocompatible arm for constructing complex architectures like dendrimers, multi-arm polymers, and bioconjugates. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and materials science sectors who require precise molecular scaffolding.

Application

• Bioconjugation and Drug Delivery: Used as a linker to attach targeting ligands, drugs, or imaging agents to nanoparticles, antibodies, or other carrier systems, enhancing solubility and circulation time.
• Dendrimer and Polymer Synthesis: Acts as a core or branching unit for creating multi-arm PEGs, star-shaped polymers, and dendrimers with controlled functionality.
• Surface Modification: Employed to functionalize surfaces (e.g., gold nanoparticles, quantum dots, biosensors) with multiple reactive groups for further coupling.
• Cross-linking Agent: Utilized in hydrogel formation and polymer network creation due to its three reactive termini, allowing for the formation of 3D matrices.
• Proteomics Research: Serves as a spacer in solid-phase peptide synthesis (SPPS) or for creating trifunctional cross-linkers for protein studies.
• Diagnostic Reagent Development: Incorporated into the design of diagnostic assays and kits where multiple detection moieties need to be attached to a central hub.

Basic Information

Product Name	Tr-Peg3
CAS No.	105589-77-3
Molecular Formula	C15H30O9
Molecular Weight	354.40 g/mol
Synonyms	1,1,1-Tris(hydroxymethyl)ethane tri(ethylene glycol) ether; Tris-PEG3; Tris(2-(2-hydroxyethoxy)ethyl)aminomethane; 2,2',2''-Nitrilotris(ethanol) triethylene glycol ether; 2,2',2''-Nitrilotriethanol tri(ethylene glycol) ether; Tris[2-(2-hydroxyethoxy)ethyl]amine; Amino tris-PEG3 alcohol
EINECS	Contact for details

Quality Control

Our Tr-Peg3 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets high-purity standards suitable for research and development. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using a desiccator or inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.