Description

trans-Dibenz(A,J)Acridine-1,2-Dihydrodiol is a high-purity, polycyclic aromatic hydrocarbon (PAH) derivative of significant interest in advanced chemical research and development. This specific dihydrodiol metabolite is a critical intermediate in the study of PAH metabolic activation pathways and their biological implications. It is primarily utilized by research institutions, analytical laboratories, and pharmaceutical development teams engaged in toxicology, environmental science, and carcinogenesis studies. The compound's defined structure makes it an essential standard and reagent for investigative work requiring precise molecular characterization.

Application

• Biochemical Research Standard: Serves as a certified reference material (CRM) for studying the metabolic pathways and DNA adduct formation of polycyclic aromatic hydrocarbons (PAHs).
• Toxicology and Carcinogenicity Studies: Used as a key intermediate in *in vitro* and *in vivo* research to understand the mechanisms of PAH-induced toxicity and cancer.
• Analytical Method Development: Employed as a high-purity standard for calibrating analytical equipment such as HPLC, GC-MS, and LC-MS in environmental and biological monitoring.
• Environmental Science: Acts as a model compound for investigating the fate, transport, and bioremediation of complex PAH contaminants in the environment.
• Pharmaceutical R&D: Utilized in early-stage discovery for screening compounds that may inhibit specific metabolic enzymes involved in procarcinogen activation.

Basic Information

Product Name	trans-Dibenz(A,J)Acridine-1,2-Dihydrodiol
CAS No.	105467-75-2
Molecular Formula	C21H15NO2
Molecular Weight	313.35 g/mol
Synonyms	trans-1,2-Dihydroxy-1,2-dihydrodibenz[a,j]acridine; DB[a,j]A-1,2-diol; 1,2-Dihydrodibenz[a,j]acridine-1,2-diol; Dibenz[a,j]acridine-1,2-dihydrodiol; PAH Dihydrodiol Metabolite; trans-DB[a,j]AC-1,2-dihydrodiol
EINECS	Contact for details

Quality Control

Every batch of trans-Dibenz(A,J)Acridine-1,2-Dihydrodiol is produced and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing, including chromatographic purity analysis and spectroscopic identification, to meet the exacting standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). For long-term stability, consider storage at -20°C under an inert atmosphere. Keep the container sealed to protect this light-sensitive compound from degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.