Description

4(3H)-Quinazolinone, 2-Ethyl-8-Hydroxy-3-Phenyl- is a high-purity, synthetically derived heterocyclic organic compound that serves as a critical advanced intermediate in modern pharmaceutical and agrochemical research. Its unique quinazolinone core structure, functionalized with ethyl, hydroxy, and phenyl groups, makes it a versatile building block for developing novel active ingredients. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for synthesizing new chemical entities with potential biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold for bioactivity.
• Chemical Biology & Proteomics: Serves as a scaffold or a tagging moiety in the design of chemical probes for studying enzyme function and protein interactions.
• Material Science Research: Investigated as a building block for organic electronic materials and metal-organic frameworks (MOFs) due to its conjugated system and coordination sites.
• Academic & Contract Research: Employed in universities and CROs (Contract Research Organizations) for methodological studies in organic synthesis and medicinal chemistry.

Basic Information

Product Name	4(3H)-Quinazolinone, 2-Ethyl-8-Hydroxy-3-Phenyl-
CAS No.	105459-52-7
Molecular Formula	C₁₆H₁₄N₂O₂
Molecular Weight	266.30 g/mol
Synonyms	2-Ethyl-8-hydroxy-3-phenyl-4(3H)-quinazolinone; 2-Ethyl-3-phenyl-8-hydroxyquinazolin-4(3H)-one; 8-Hydroxy-2-ethyl-3-phenyl-3,4-dihydroquinazolin-4-one; 3-Phenyl-2-ethyl-8-hydroxy-4(3H)-quinazolinone; 105459-52-7; Quinazolin-4(3H)-one, 2-ethyl-8-hydroxy-3-phenyl-
EINECS	Contact for details

Quality Control

Our 4(3H)-Quinazolinone, 2-Ethyl-8-Hydroxy-3-Phenyl- is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our standard is to meet or exceed the specifications required for advanced research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.