Description

3R,4R-Dihydroxy-3,4-Dihydro-Dibenzanthracene is a high-purity, stereospecific dihydrodiol derivative of dibenzanthracene, a polycyclic aromatic hydrocarbon (PAH) of significant research interest. This compound serves as a critical advanced synthetic intermediate and a reference standard in the study of metabolic pathways, carcinogenesis, and environmental toxicology. It is primarily utilized by research institutions, pharmaceutical R&D departments, and analytical laboratories focusing on PAH biochemistry and metabolite analysis.

Application

• Biochemical Research: Used as a key intermediate in studying the metabolic activation and detoxification pathways of polycyclic aromatic hydrocarbons (PAHs).
• Toxicology Studies: Serves as a precise reference standard for investigating the carcinogenic mechanisms and DNA adduct formation of dibenzanthracene metabolites.
• Pharmaceutical Development: Acts as a building block or a metabolite analog in the synthesis and testing of potential chemopreventive or therapeutic agents.
• Analytical Chemistry: Employed as a high-purity calibrant or standard in chromatographic (HPLC, GC) and spectroscopic methods for accurate quantification and identification.
• Environmental Science: Used in research to understand the environmental fate, biodegradation, and human exposure risks associated with PAH pollutants.

Basic Information

Product Name	3R,4R-Dihydroxy-3,4-Dihydro-Dibenzanthracene
CAS No.	105453-64-3
Molecular Formula	C22H16O2
Molecular Weight	312.36 g/mol
Synonyms	(3R,4R)-3,4-Dihydroxy-3,4-dihydrodibenz[a,h]anthracene; 3,4-Dihydro-3,4-dihydroxydibenzanthracene (3R,4R-form); (+)-(3R,4R)-Dihydroxy-3,4-dihydrodibenz[a,h]anthracene; Dibenz[a,h]anthracene 3,4-dihydrodiol (3R,4R-isomer); DBA 3,4-diol; DB[a,h]A-3,4-dihydrodiol
EINECS	Contact for details

Quality Control

Our 3R,4R-Dihydroxy-3,4-Dihydro-Dibenzanthracene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity verification, to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific analytical data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This compound is light-sensitive and easily oxidized; prolonged exposure to air or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee (3R,4R)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.