Description

trans-2-(4-(tert-Butyl)Phenyl)Cyclopropane-1-Carboxylic Acid is a high-purity, synthetically valuable cyclopropane derivative. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, prized for its rigid, three-membered ring structure which imparts unique steric and electronic properties to target molecules. It is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to develop novel active ingredients with enhanced efficacy and stability.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of antiviral, anti-inflammatory, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the cyclopropane moiety can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to achieve high enantioselectivity.
• Material Science Research: Employed in the synthesis of specialty monomers and polymers with tailored thermal and mechanical properties.
• Fine Chemical Production: Acts as a building block for complex fragrance molecules, flavors, and other high-value specialty chemicals.

Basic Information

Product Name	trans-2-(4-(tert-Butyl)Phenyl)Cyclopropane-1-Carboxylic Acid
CAS No.	105393-30-4
Molecular Formula	C14H18O2
Molecular Weight	218.29 g/mol
Synonyms	(1R,2S)-rel-2-[4-(1,1-Dimethylethyl)phenyl]cyclopropanecarboxylic Acid; (1R,2S)-2-(4-tert-Butylphenyl)cyclopropanecarboxylic Acid; trans-2-(p-tert-Butylphenyl)cyclopropanecarboxylic Acid; 2-(4-tert-Butylphenyl)cyclopropanecarboxylic Acid; 105393-30-4; p-tert-Butyl-trans-phenylcyclopropanecarboxylic Acid
EINECS	Contact for details

Quality Control

Our trans-2-(4-(tert-Butyl)Phenyl)Cyclopropane-1-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the high standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.