Description

1-Pyrenemethyl-3-Hydroxy-22,23-Bisnor-5-Cholenate is a high-purity, synthetic steroidal derivative functionalized with a pyrene fluorophore. This compound is critical for advanced research and development, particularly in the fields of biochemistry and materials science, where its unique structure enables precise molecular probing and labeling. It is primarily utilized by research institutions, pharmaceutical developers, and specialty chemical manufacturers working on fluorescence-based assays, molecular probes, and novel material synthesis.

Application

• Fluorescent Labeling Agent: Used as a derivatization reagent for the sensitive detection and quantification of sterols and related compounds via HPLC or LC-MS.
• Biochemical Research Probe: Serves as a critical tool in studying lipid membrane dynamics, protein-sterol interactions, and intracellular trafficking mechanisms.
• Pharmaceutical Intermediate: Acts as a key synthetic building block in the research and development of novel therapeutic agents and diagnostic molecules.
• Material Science Applications: Employed in the development of advanced organic electronic materials and sensors due to the photophysical properties of the pyrene moiety.
• Analytical Reference Standard: Provides a high-purity standard for method development and validation in analytical laboratories.

Basic Information

Product Name	1-Pyrenemethyl-3-Hydroxy-22,23-Bisnor-5-Cholenate
CAS No.	105344-74-9
Molecular Formula	C₃₉H₄₈O₃
Molecular Weight	564.80 g/mol
Synonyms	22,23-Bisnor-5-cholenic acid, 3-hydroxy-, 1-pyrenylmethyl ester; 3-Hydroxy-22,23-bisnor-5-cholenic acid 1-pyrenylmethyl ester; Pyrenylmethyl cholenate derivative; Fluorescent sterol probe; 1-Pyrenemethyl cholenate; PM-Cholenate
EINECS	Contact for details

Quality Control

Our 1-Pyrenemethyl-3-Hydroxy-22,23-Bisnor-5-Cholenate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.