Description

Rac-6-Fluoro-3,4-Dihydro-4-Oxo-2H-1-Benzopyran-2-Carboxylic Acid is a key fluorinated coumarin derivative that serves as a versatile synthetic intermediate in advanced organic chemistry. Its value lies in the strategic incorporation of fluorine, which is critical for modulating the biological activity and physicochemical properties of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and exploring structure-activity relationships.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting enzymes and receptors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, where the fluorine atom enhances lipophilicity and metabolic stability.
• Fluorinated Coumarin Synthesis: Serves as a core scaffold for creating a library of fluorinated coumarin derivatives for various biological and material science studies.
• Chemical Biology Probes: Utilized in the design and synthesis of fluorescent probes and activity-based protein profiling (ABPP) agents due to the coumarin core.
• Organic Synthesis Building Block: Employed in complex organic synthesis, including cyclization reactions and the preparation of heterocyclic compounds.
• Material Science Precursor: Investigated as a monomer or precursor for advanced organic materials, such as polymers with specific optical properties.

Basic Information

Product Name	Rac-6-Fluoro-3,4-Dihydro-4-Oxo-2H-1-Benzopyran-2-Carboxylic Acid
CAS No.	105300-40-1
Molecular Formula	C10H7FO4
Molecular Weight	210.16 g/mol
Synonyms	6-Fluorochroman-2-carboxylic acid-4-one; (±)-6-Fluoro-3,4-dihydro-4-oxo-2H-1-benzopyran-2-carboxylic acid; 6-Fluoro-4-oxochroman-2-carboxylic acid; 6-Fluoro-4-oxo-2H-chromene-2-carboxylic acid; 2H-1-Benzopyran-2-carboxylic acid, 6-fluoro-3,4-dihydro-4-oxo-; rac-6-Fluoro-4-oxochroman-2-carboxylic acid; 6-Fluoro-4-oxo-3,4-dihydro-2H-chromene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of Rac-6-Fluoro-3,4-Dihydro-4-Oxo-2H-1-Benzopyran-2-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is characterized using advanced analytical techniques including HPLC, NMR, and MS to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect from moisture. Store away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.