Description

tert-Butyl (5-Amino-4,4-Dimethylpentyl)Carbamate is a protected amino acid derivative, specifically a Boc-protected amine, serving as a critical building block in advanced organic synthesis. This compound matters because it provides a versatile and stable intermediate for constructing complex molecules, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists for the synthesis of peptide mimetics, active pharmaceutical ingredients (APIs), and other bioactive compounds where precise amine functionality is required.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Peptidomimetic Synthesis: Used in the construction of peptide analogs and mimetics to enhance metabolic stability and bioavailability.
• Protecting Group Strategy: The tert-butyloxycarbonyl (Boc) group protects the amine functionality during multi-step synthetic sequences.
• Medicinal Chemistry Research: Employed in lead optimization and structure-activity relationship (SAR) studies.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs producing specialized fine chemicals.
• Bioconjugation: Potential use in linker chemistry for antibody-drug conjugates (ADCs) and other bioconjugates.

Basic Information

Product Name	tert-Butyl (5-Amino-4,4-Dimethylpentyl)Carbamate
CAS No.	105090-82-2
Molecular Formula	C12H25NO2
Molecular Weight	215.33 g/mol
Synonyms	5-Amino-4,4-dimethylpentyl-carbamic acid tert-butyl ester; 1,1-Dimethyl-4-[(tert-butoxycarbonyl)amino]butylamine; Boc-5-amino-4,4-dimethylpentylamine; N-Boc-5-amino-4,4-dimethylpentylamine; tert-Butyl N-(5-amino-4,4-dimethylpentyl)carbamate; 4,4-Dimethyl-5-[(tert-butoxycarbonyl)amino]pentan-1-amine; (5-Amino-4,4-dimethylpentyl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl (5-Amino-4,4-Dimethylpentyl)Carbamate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and identity. Certificates of Analysis (COA) detailing all specifications are available upon request. We adhere to cGMP standards where applicable to support our clients in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.