Description

1,2-Bis(Aminooxy)Ethane Dihydrochloride is a versatile bifunctional aminooxy compound, primarily used as a key linker and building block in advanced organic synthesis. Its value lies in its ability to form stable oxime bonds with carbonyl groups, enabling precise bioconjugation and material functionalization. This product is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and materials science sectors, particularly for developing antibody-drug conjugates (ADCs), modifying biomolecules, and creating functionalized polymers.

Application

• Bioconjugation Reagent: A critical linker for the site-specific conjugation of drugs, dyes, or other payloads to antibodies, proteins, and peptides, forming stable oxime linkages.
• Antibody-Drug Conjugate (ADC) Development: Serves as a fundamental chemical bridge in the synthesis of novel ADCs, connecting cytotoxic agents to targeting antibodies.
• Surface Functionalization: Used to modify surfaces, nanoparticles, and polymers by introducing aminooxy groups for subsequent attachment of biomolecules or other functional units.
• Crosslinking Agent: Facilitates the crosslinking of polymers or biomolecules containing aldehyde or ketone functionalities.
• Chemical Biology Tool: Enables the study of biomolecular interactions and cellular processes through selective labeling and tagging strategies.
• Pharmaceutical Intermediate: Acts as a key synthetic intermediate in the production of more complex therapeutic agents and diagnostic compounds.

Basic Information

Product Name	1,2-Bis(Aminooxy)Ethane Dihydrochloride
CAS No.	104845-83-2
Molecular Formula	C4H12N2O2 · 2HCl
Molecular Weight	209.07 g/mol
Synonyms	1,2-Diaminooxyethane Dihydrochloride; Ethane-1,2-diyldioxybis(azanide) Dihydrochloride; N,N'-Dihydroxy-1,2-ethanediamine Dihydrochloride; 1,2-Bis(hydroxyamino)ethane Dihydrochloride; 1,2-Ethylenediamine-N,N'-dioxide Dihydrochloride; Aminooxy-PEG2-Aminooxy Dihydrochloride; Bis-Aminooxy-PEG Dihydrochloride; O,O'-(Ethane-1,2-diyl)bis(hydroxylamine) Dihydrochloride
EINECS	Contact for details

Quality Control

Our 1,2-Bis(Aminooxy)Ethane Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and pharmaceutical-grade intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.