Description

5-Bromo-8-Fluoro-1,2,3,4-Tetrahydronaphthalene is a high-purity, multi-functional halogenated tetrahydronaphthalene derivative. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis, enabling the development of novel active molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science sectors for creating complex chemical architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Synthesis: Used in the synthesis of novel herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Organic Light-Emitting Diode (OLED) Materials: Acts as a precursor for electron-transport or host materials in the development of advanced display and lighting technologies.
• Ligand and Catalyst Development: Serves as a backbone for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Chemical Research: Employed in academic and industrial R&D for studying structure-activity relationships (SAR) and novel organic reactions.
• Fluorinated Compound Library Synthesis: A valuable building block for constructing diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	5-Bromo-8-Fluoro-1,2,3,4-Tetrahydronaphthalene
CAS No.	104761-49-1
Molecular Formula	C10H9BrF
Molecular Weight	229.08 g/mol
Synonyms	5-Bromo-8-fluoro-1,2,3,4-tetrahydronaphthalene; 1,2,3,4-Tetrahydronaphthalene, 5-bromo-8-fluoro-; 8-Fluoro-5-bromo-1,2,3,4-tetrahydronaphthalene; 5-Bromo-8-fluoro-tetralin; 5-Br-8-F-Tetralin; 104761-49-1 (CAS); Tetralin, 5-bromo-8-fluoro-
EINECS	Contact for details

Quality Control

Our 5-Bromo-8-Fluoro-1,2,3,4-Tetrahydronaphthalene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.