Description

(R)-(＋)-5’-Methoxylaudanosine is a chiral alkaloid derivative of laudanosine, characterized by its specific stereochemistry at the R-configuration and a methoxy substitution. This compound is a critical chiral building block and reference standard in advanced pharmaceutical research and asymmetric synthesis. It is primarily utilized by research scientists and process chemists in the pharmaceutical, biotechnology, and fine chemical industries for developing novel therapeutics and studying receptor interactions.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of potential active pharmaceutical ingredients (APIs), particularly for neurological and cardiovascular targets.
• Asymmetric Synthesis: Employed as a chiral ligand or auxiliary in catalytic reactions to induce stereoselectivity.
• Biochemical Research: Used as a reference standard and tool compound in pharmacological studies, especially those involving opioid or muscarinic receptors.
• Analytical Standard: Essential for method development and quality control (HPLC, GC, LC-MS) in laboratories to ensure purity and identity of related compounds.
• Process Development: Utilized in scaling up synthetic routes for complex molecules in fine chemical and custom manufacturing settings.

Basic Information

Product Name	(R)-(＋)-5’-Methoxylaudanosine
CAS No.	104758-49-8
Molecular Formula	C22H29NO5
Molecular Weight	387.47 g/mol
Synonyms	(R)-5'-Methoxylaudanosine; (R)-(+)-5'-Methoxylaudanosine; (R)-1-[(3,4-Dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline; (R)-Laudanosine, 5'-methoxy-; (R)-N-Methylcoclaurine 3',4',6,7-tetramethyl ether
EINECS	Contact for details

Quality Control

Our (R)-(＋)-5’-Methoxylaudanosine is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to relevant industry standards for research-grade chemicals, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.