Description

5-Bromo-2-Hydroxynicotinic Acid is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a bromine substituent and a carboxylic acid group, makes it a valuable intermediate for constructing complex molecules with high precision. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other biologically active heterocycles.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Building block for synthesizing functional organic materials and metal-organic frameworks (MOFs).
• Chemical Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	5-Bromo-2-Hydroxynicotinic Acid
CAS No.	104612-36-4
Molecular Formula	C6H4BrNO3
Molecular Weight	218.01 g/mol
Synonyms	5-Bromo-2-hydroxypyridine-3-carboxylic acid; 2-Hydroxy-5-bromonicotinic acid; 3-Carboxy-5-bromo-2-hydroxypyridine; 5-Bromo-2-pyridone-3-carboxylic acid; 5-Bromo-2-oxo-1,2-dihydropyridine-3-carboxylic acid; 5-Bromo-3-pyridinecarboxylic acid, 2-hydroxy-; 104612-36-4
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Hydroxynicotinic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product may be light-sensitive and hygroscopic; keep the container tightly sealed when not in use to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.