Description

(1R,3S)-3-[(1Z)-2-Chloro-3,3,3-Trifluoro-1-Propen-1-Yl]-2,2-Dimethylcyclopropanecarboxylic Acid is a high-purity, advanced chiral intermediate of significant commercial importance in the fine chemical and agrochemical sectors. Its core value lies in its role as a critical building block for the synthesis of complex, biologically active molecules, particularly modern pyrethroid insecticides. This compound is essential for manufacturers and R&D organizations focused on developing and producing next-generation crop protection agents and other specialty chemicals requiring precise stereochemistry.

Application

• Key Intermediate for Pyrethroid Insecticides: Serves as a crucial precursor in the synthesis of high-performance, third-generation pyrethroids like β-cyfluthrin and other halogenated analogs.
• Agrochemical Active Ingredient (AI) Synthesis: Used in the research, development, and commercial-scale manufacturing of novel agrochemical active ingredients with enhanced efficacy and environmental profiles.
• Chiral Building Block in Fine Chemicals: Employed in asymmetric synthesis for constructing complex molecular architectures in pharmaceuticals and other specialty chemicals where stereochemical purity is paramount.
• Research & Development (R&D): Utilized in academic and industrial laboratories for exploring new synthetic pathways and developing novel compounds with insecticidal or other biological activities.
• Process Chemistry & Scale-Up: Critical for process optimization and pilot-to-commercial scale production runs in contract manufacturing organizations (CMOs) and integrated chemical companies.

Basic Information

Product Name	(1R,3S)-3-[(1Z)-2-Chloro-3,3,3-Trifluoro-1-Propen-1-Yl]-2,2-Dimethylcyclopropanecarboxylic Acid
CAS No.	104531-15-9
Molecular Formula	C10H11ClF3O2
Molecular Weight	254.64 g/mol
Synonyms	(1R,3S)-3-[(1Z)-2-Chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid; (Z)-(1R,3S)-2,2-Dimethyl-3-[(2-chloro-3,3,3-trifluoro-1-propenyl)]cyclopropanecarboxylic Acid; β-Cyfluthrin Acid; Baythroid Acid Intermediate; (1R,3S)-cis-3-(Z-2-Chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanecarboxylic Acid; (Z)-(1R,3S)-3-(2-Chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethylcyclopropanecarboxylic Acid
EINECS	Contact for details

Quality Control

Our production of (1R,3S)-3-[(1Z)-2-Chloro-3,3,3-Trifluoro-1-Propen-1-Yl]-2,2-Dimethylcyclopropanecarboxylic Acid adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure it meets exacting specifications for use in advanced synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to guarantee traceability and support your regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids, organic solvents, fluorides, and strong alkalis. For long-term storage, consider inert atmosphere conditions to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.