Description

1-{2-[2-(2-{2-[2-(2-Bromo-Ethoxy)-Ethoxy]-Ethoxy}-Ethoxy)-Ethoxy]-Ethoxy}-2-Methoxy-Ethane is a specialized, high-purity polyethylene glycol (PEG) derivative featuring a terminal bromo group and a methoxy capping agent. This unique bifunctional structure makes it a critical intermediate for advanced organic synthesis, enabling precise chemical modifications and polymer functionalization. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for applications such as drug conjugation, polymer cross-linking, and surface modification.

Application

• Pharmaceutical Intermediate: Used as a key building block in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs, particularly for conjugation strategies.
• Bioconjugation Linker: Serves as a heterobifunctional cross-linker for attaching drugs, dyes, or other molecules to proteins, antibodies, or nanoparticles (PEGylation).
• Polymer Chemistry: Acts as a macro-initiator or functional monomer for the synthesis of block copolymers and functionalized polymeric materials.
• Surface Modification: Employed to create hydrophilic, non-fouling coatings on medical devices, sensors, and diagnostic platforms.
• Material Science: Utilized in the development of hydrogels, dendrimers, and other advanced nanostructured materials.
• Chemical Research: A valuable reagent in organic synthesis for introducing PEG spacers or bromoalkyl functionalities into target molecules.

Basic Information

Product Name	1-{2-[2-(2-{2-[2-(2-Bromo-Ethoxy)-Ethoxy]-Ethoxy}-Ethoxy)-Ethoxy]-Ethoxy}-2-Methoxy-Ethane
CAS No.	104518-25-4
Molecular Formula	C17H35BrO8
Molecular Weight	447.36 g/mol
Synonyms	2-[2-[2-[2-[2-(2-Bromoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethyl methyl ether; Bromo-PEG7-methyl ether; Br-PEG7-OMe; 1-Bromo-3,6,9,12,15,18,21-heptaoxatricosane; 2-Methoxyethyl octaethylene glycol monobromide; α-Bromo-ω-methoxyhepta(ethylene glycol); Heptaethylene glycol monomethyl ether monobromide; mPEG7-Br
EINECS	Contact for details

Quality Control

Our high-purity 1-{2-[2-(2-{2-[2-(2-Bromo-Ethoxy)-Ethoxy]-Ethoxy}-Ethoxy)-Ethoxy]-Ethoxy}-2-Methoxy-Ethane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and titration, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting applications in GMP-sensitive environments and research.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. Keep the container in a cool, dry, well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Bromine Content	Conforms to theoretical

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.