Description

2-[(Prop-2-Yn-1-Yl)Amino]Acetic Acid Hydrochloride is a specialized organic salt featuring a terminal alkyne functional group, making it a valuable building block in advanced chemical synthesis. Its primary commercial value lies in its role as a key intermediate for the development of pharmaceuticals, agrochemicals, and novel materials. This compound is particularly sought after by research institutions and industrial manufacturers engaged in medicinal chemistry, peptide modification, and click chemistry applications.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting neurological and oncological pathways.
• Peptide Chemistry & Bioconjugation: Used to introduce alkyne handles onto peptides or proteins, enabling subsequent site-specific modification via copper-catalyzed azide-alkyne cycloaddition (CuAAC) click chemistry.
• Agrochemical Research: Serves as a building block for developing novel herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Material Science: Employed in the creation of functionalized polymers, dendrimers, and surface coatings where the alkyne group facilitates cross-linking or property modification.
• Chemical Biology Probes: Integral for synthesizing molecular probes and tags used in cellular imaging and target identification studies.
• Academic & Contract Research: A standard reagent in university and CRO laboratories for method development and exploratory synthesis in organic chemistry.

Basic Information

Product Name	2-[(Prop-2-Yn-1-Yl)Amino]Acetic Acid Hydrochloride
CAS No.	104501-33-9
Molecular Formula	C5H8ClNO2
Molecular Weight	149.57 g/mol
Synonyms	Propargylglycine Hydrochloride; N-Propargylglycine Hydrochloride; 2-(Prop-2-yn-1-ylamino)acetic acid hydrochloride; (Prop-2-yn-1-ylamino)acetic acid hydrochloride; Glycine, N-2-propynyl-, hydrochloride; 2-(Prop-2-ynylamino)acetic acid hydrochloride; Aminoacetic acid, N-2-propynyl-, hydrochloride
EINECS	Contact for details

Quality Control

Our production of 2-[(Prop-2-Yn-1-Yl)Amino]Acetic Acid Hydrochloride adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and reliability. Each lot is analyzed to confirm identity, purity, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay (by HPLC), residual solvents, and related substances is provided with every shipment. We operate under a cGMP-compliant quality management system suitable for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.