Description

7-(Phenylacetamido)-4-(Trifluoromethyl)Coumarin is a specialized fluorinated coumarin derivative that serves as a critical building block and analytical reagent in advanced chemical synthesis. Its unique structure, combining a coumarin core with phenylacetamide and trifluoromethyl groups, provides valuable photophysical and biochemical properties. This compound is essential for researchers and manufacturers in pharmaceutical development, agrochemical research, and materials science, particularly for applications requiring fluorescence labeling or as a precursor for more complex heterocyclic systems.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting enzymes where the coumarin scaffold is active.
• Fluorescent Probe & Labeling Agent: Used in biochemical assays and diagnostic development due to its inherent fluorescence properties from the coumarin core.
• Agrochemical Research: Serves as a building block for developing new active ingredients with enhanced properties conferred by the trifluoromethyl group.
• Organic Light-Emitting Diode (OLED) Materials: Investigated as an electron-transport or emissive layer component in advanced electronic materials.
• Chemical Biology Tool: Utilized in activity-based protein profiling (ABPP) and other mechanistic studies in life sciences.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and photochemistry.

Basic Information

Product Name	7-(Phenylacetamido)-4-(Trifluoromethyl)Coumarin
CAS No.	104145-35-9
Molecular Formula	C19H12F3NO3
Molecular Weight	359.30 g/mol
Synonyms	4-(Trifluoromethyl)-7-(phenylacetamido)coumarin; 7-(Phenylacetamido)-4-trifluoromethylcoumarin; 7-Phenylacetamido-4-trifluoromethyl-2H-chromen-2-one; 7-(2-Phenylacetamido)-4-(trifluoromethyl)-2H-chromen-2-one; Phenylacetamido-trifluoromethylcoumarin; 7-PAC-TFC; Coumarin 7-phenylacetamido-4-trifluoromethyl
EINECS	Contact for details

Quality Control

Our 7-(Phenylacetamido)-4-(Trifluoromethyl)Coumarin is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, which includes data from HPLC, NMR, and mass spectrometry. Our quality protocols are designed to meet the stringent requirements of research and development applications across global markets.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.