Description

4-(4-Acetylpiperazin-1-Yl)Benzoic Acid is a high-purity organic building block featuring a benzoic acid core linked to an acetylpiperazine moiety. This compound matters as a versatile and critical intermediate in modern pharmaceutical research and development, enabling the synthesis of complex molecules with targeted biological activity. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for creating novel drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for neurological and psychiatric drug discovery.
• Chemical Biology Probe Development: Used to create tool compounds for studying biological pathways and target validation in research settings.
• Ligand Synthesis for Drug Discovery: Serves as a precursor for creating ligands with potential affinity for various G-protein coupled receptors (GPCRs) and enzymes.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to introduce specific functional groups and molecular complexity.
• Academic & Contract Research: Utilized in university laboratories and CROs (Contract Research Organizations) for exploratory chemistry and method development.

Basic Information

Product Name	4-(4-Acetylpiperazin-1-Yl)Benzoic Acid
CAS No.	104080-55-9
Molecular Formula	C13H16N2O3
Molecular Weight	248.28 g/mol
Synonyms	4-(4-Acetyl-1-piperazinyl)benzoic acid; 1-[4-(Carboxyphenyl)]-4-acetylpiperazine; Benzoic acid, 4-(4-acetyl-1-piperazinyl)-; 4-(N-Acetylpiperazino)benzoic acid; 4-(4-Acetylpiperazino)benzoic acid; 4-(4-Acetyl-piperazin-1-yl)-benzoic acid; 104080-55-9; 4-Carboxyphenyl-4-acetylpiperazine
EINECS	Contact for details

Quality Control

Our 4-(4-Acetylpiperazin-1-Yl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.