Description

8-Ethynylquinoline is a versatile heterocyclic building block featuring a quinoline core functionalized with an ethynyl group. This compound is valued for its role as a key intermediate in the synthesis of complex organic molecules, particularly in pharmaceutical research and materials science. It is essential for researchers and manufacturers in the fields of medicinal chemistry, agrochemicals, and advanced material development.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, especially those targeting neurological disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging the biological activity of the quinoline scaffold.
• Material Science: Acts as a monomer or cross-linking agent in the creation of conductive polymers, organic semiconductors, and metal-organic frameworks (MOFs).
• Catalyst Ligand: The ethynyl and nitrogen moieties make it a potential ligand for transition metal catalysts used in coupling reactions.
• Fluorescent Probe Development: Utilized in the design of chemosensors and bio-imaging agents due to the inherent fluorescence properties of quinoline derivatives.
• Academic & Industrial R&D: A fundamental reagent for exploring new organic reactions and constructing complex molecular architectures in research laboratories.

Basic Information

Product Name	8-Ethynylquinoline
CAS No.	103987-81-1
Molecular Formula	C11H7N
Molecular Weight	153.18 g/mol
Synonyms	Quinolin-8-ylethyne; 8-Quinolinylethyne; 8-(Ethynyl)quinoline; 1-(Quinolin-8-yl)ethyne; Ethynylquinoline; 8-Ethynyl-quinoline; 8-Ethynyl-chinolin
EINECS	Contact for details

Quality Control

Our 8-Ethynylquinoline is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.