Description

5-Ethynylquinoline is a high-value, functionalized heterocyclic building block characterized by its terminal alkyne group. This compound is essential for advanced organic synthesis, particularly in metal-catalyzed cross-coupling reactions like the Sonogashira reaction. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex molecular architectures in drug discovery, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the synthesis of novel crop protection agents and herbicides with enhanced efficacy.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands in catalysis and coordination chemistry.
• Material Science: Employed in the development of organic semiconductors, luminescent materials, and advanced polymers.
• Chemical Biology: Useful as a tagging or labeling agent in bioconjugation and probe development due to its reactive alkyne handle.
• Academic & Industrial R&D: A versatile building block for methodological development and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	5-Ethynylquinoline
CAS No.	103987-79-7
Molecular Formula	C11H7N
Molecular Weight	153.18 g/mol
Synonyms	5-Ethynylquinoline; Quinoline, 5-ethynyl-; 5-Ethynyl-quinoline; 5-(Ethynyl)quinoline; 103987-79-7
EINECS	Contact for details

Quality Control

Our 5-Ethynylquinoline is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This compound is easily oxidized and light-sensitive.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.