Description

2-Fluoro-5-Nitro-Biphenyl is a high-purity fluorinated biphenyl derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine and nitro functional groups, which are essential for modulating the electronic and steric properties of target molecules. This compound is primarily needed by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a core structure in the design of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, improving charge transport and thermal stability.
• Organic Synthesis Building Block: A versatile reagent for Suzuki-Miyaura and other cross-coupling reactions to construct complex biaryl systems for material science applications.
• Chemical Research & Development: Employed in academic and industrial labs for method development and exploring new reaction pathways involving fluorinated aromatics.

Basic Information

Product Name	2-Fluoro-5-Nitro-Biphenyl
CAS No.	103977-87-3
Molecular Formula	C12H8FNO2
Molecular Weight	217.20 g/mol
Synonyms	2-Fluoro-5-nitrobiphenyl; 1-Fluoro-4-(2-nitrophenyl)benzene; 2'-Fluoro-5'-nitro-1,1'-biphenyl; (2-Fluorophenyl)(2-nitrophenyl); Biphenyl, 2-fluoro-5-nitro-; 2-Nitro-2'-fluorobiphenyl
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Nitro-Biphenyl is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.