Description

(R)-2-Amino-2-(2-Methoxyphenyl)Acetic Acid Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate of significant commercial importance. Its enantiomeric purity makes it a critical precursor in the synthesis of active pharmaceutical ingredients (APIs) and fine chemicals where stereochemistry is essential for biological activity. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel therapeutics, particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Synthesis: Used as a starting material or resolving agent in catalytic asymmetric reactions to produce enantiomerically pure compounds.
• Peptidomimetics Research: Serves as a constrained amino acid analog in the design and synthesis of peptide-like molecules for drug discovery.
• Agrochemical Development: Employed in the research and production of chiral pesticides and herbicides where specific stereoisomers exhibit enhanced activity.
• Ligand Synthesis: Useful for preparing chiral ligands used in metal-catalyzed reactions and coordination chemistry.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry and process development.

Basic Information

Product Name	(R)-2-Amino-2-(2-Methoxyphenyl)Acetic Acid Hydrochloride
CAS No.	103889-79-8
Molecular Formula	C9H12ClNO3
Molecular Weight	217.65 g/mol
Synonyms	(R)-2-Amino-2-(2-Methoxyphenyl)acetic acid hydrochloride; (R)-2-Methoxy-D-phenylglycine hydrochloride; (R)-O-Methyl-D-phenylglycine hydrochloride; D-2-Methoxyphenylglycine hydrochloride; (R)-α-Amino-2-methoxyphenylacetic acid hydrochloride; (2R)-2-Amino-2-(2-methoxyphenyl)acetic acid hydrochloride; (R)-2-(2-Methoxyphenyl)glycine hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-2-Amino-2-(2-Methoxyphenyl)Acetic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.