Description

Boc-p-Iodo-Dl-Phe-Oh is a protected amino acid derivative, specifically a para-iodinated phenylalanine analog with a tert-butoxycarbonyl (Boc) protecting group on the amine. This compound is a crucial building block in the synthesis of complex peptides and peptidomimetics, where it introduces iodine atoms for further functionalization via cross-coupling reactions. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and agrochemical sectors for drug discovery, medicinal chemistry, and the development of novel bioactive compounds.

Application

• Pharmaceutical Intermediates: A key synthon for the solid-phase and solution-phase synthesis of peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry & Drug Discovery: Used to incorporate iodine handles into peptide scaffolds for structure-activity relationship (SAR) studies and for further derivatization via palladium-catalyzed cross-coupling (e.g., Suzuki, Sonogashira).
• Bioconjugation & Probe Development: Serves as a precursor for synthesizing radiolabeled (e.g., with I-125) or fluorescently tagged peptides for diagnostic imaging and biochemical assays.
• Agrochemical Research: Employed in the design and synthesis of novel peptide-inspired bioactive molecules for crop protection.
• Academic & Contract Research: Essential reagent in university and CRO laboratories for exploring new synthetic methodologies and creating specialized peptide libraries.

Basic Information

Product Name	Boc-p-Iodo-Dl-Phe-Oh
CAS No.	103882-09-3
Molecular Formula	C₁₄H₁₈INO₄
Molecular Weight	391.20 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-4-iodo-DL-phenylalanine; Boc-4-Iodo-DL-phenylalanine; (±)-N-Boc-4-iodophenylalanine; tert-Butyl (4-iodophenyl)alaninate; Boc-Phe(4-I)-OH; DL-4-Iodo-N-Boc-phenylalanine; N-Boc-para-iodo-DL-phenylalanine
EINECS	Contact for details

Quality Control

Our Boc-p-Iodo-Dl-Phe-Oh CAS NO 103882-09-3 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring reliable and consistent building blocks for research and cGMP-compliant development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.