Description

Ethyl 7-Chloro-8-Methyl-4-Oxo-1,4-Dihydroquinoline-3-Carboxylate is a high-purity, synthetically valuable organic intermediate belonging to the 4-quinolone family. This compound is a critical building block in the synthesis of advanced pharmaceutical agents, particularly those with antibacterial or other targeted biological activities. It is essential for research and development chemists and manufacturers in the pharmaceutical and fine chemical industries seeking to develop novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinolone-based antibiotics and other therapeutic agents.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core scaffold for medicinal chemistry research and the development of new drug candidates.
• Fine Chemical Synthesis: Used in multi-step organic syntheses to construct complex molecules for research and industrial applications.
• Biochemical Research: Employed in studies investigating enzyme inhibition, receptor binding, and other biological mechanisms.
• Chemical Reference Standard: Utilized as a high-purity standard for analytical method development and quality control in pharmaceutical manufacturing.

Basic Information

Product Name	Ethyl 7-Chloro-8-Methyl-4-Oxo-1,4-Dihydroquinoline-3-Carboxylate
CAS No.	103877-51-6
Molecular Formula	C₁₃H₁₂ClNO₃
Molecular Weight	265.69 g/mol
Synonyms	7-Chloro-8-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid ethyl ester; Ethyl 7-chloro-8-methyl-4-oxo-1,4-dihydro-3-quinolinecarboxylate; 1,4-Dihydro-7-chloro-8-methyl-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester; 3-Carbethoxy-7-chloro-8-methyl-4(1H)-quinolone; 7-Chloro-8-methyl-4(1H)-oxoquinoline-3-carboxylic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl 7-Chloro-8-Methyl-4-Oxo-1,4-Dihydroquinoline-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles suitable for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.