Description

8-Amino-5,6,7,8-Tetrahydronaphthalen-2-Ol CAS NO 103791-24-8 is a versatile tetralin derivative, serving as a key chiral building block and intermediate in advanced organic synthesis. Its unique fused-ring structure with both amino and phenolic hydroxyl functional groups makes it valuable for constructing complex molecular architectures. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators.
• Chiral Ligand & Catalyst Development: Serves as a starting material for creating chiral auxiliaries, ligands for asymmetric catalysis, and organocatalysts.
• Dye & Pigment Intermediate: Employed in the synthesis of specialized dyes, pigments, and optical brighteners due to its naphthalene core.
• Material Science Research: Investigated as a monomer or functional component in the development of advanced polymers and organic electronic materials.
• Chemical Research & Development: A valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	8-Amino-5,6,7,8-Tetrahydronaphthalen-2-Ol
CAS No.	103791-24-8
Molecular Formula	C₁₀H₁₃NO
Molecular Weight	163.22 g/mol
Synonyms	8-Amino-5,6,7,8-tetrahydro-2-naphthol; 2-Naphthol, 8-amino-5,6,7,8-tetrahydro-; 5,6,7,8-Tetrahydro-8-amino-2-naphthol; 8-Amino-1,2,3,4-tetrahydronaphthalen-2-ol; 8-Amino-5,6,7,8-tetrahydronaphthalen-2-ol; 8-Amino-5,6,7,8-tetrahydro-2-hydroxynaphthalene; 2-Hydroxy-8-amino-1,2,3,4-tetrahydronaphthalene
EINECS	Contact for details

Quality Control

Our 8-Amino-5,6,7,8-Tetrahydronaphthalen-2-Ol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, purity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.