Description

1-Cyano-6-Methoxy-5-(Trifluoromethyl)Naphthalene is a high-value, multi-functional naphthalene derivative distinguished by its trifluoromethyl and cyano substituents. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis. It is essential for research and production in the pharmaceutical, agrochemical, and advanced materials sectors, where its unique structure enables the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, anti-inflammatory agents, and oncology therapeutics.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the biological activity of the trifluoromethyl group.
• Organic Light-Emitting Diodes (OLEDs): Acts as an electron-transport or host material in the fabrication of OLED devices due to its naphthalene core and electron-withdrawing groups.
• Liquid Crystal Materials: Serves as a building block for high-performance liquid crystal compounds used in display technologies.
• Fluorescent Dyes and Sensors: Utilized in the development of specialized fluorescent probes and molecular sensors for analytical chemistry and bio-imaging.
• Cross-Coupling Reactions: An important substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) for constructing complex organic architectures.

Basic Information

Product Name	1-Cyano-6-Methoxy-5-(Trifluoromethyl)Naphthalene
CAS No.	103604-49-5
Molecular Formula	C₁₃H₈F₃NO
Molecular Weight	251.21 g/mol
Synonyms	5-(Trifluoromethyl)-6-methoxy-1-naphthalenecarbonitrile; 6-Methoxy-5-(trifluoromethyl)-1-naphthonitrile; 1-Naphthalenecarbonitrile, 6-methoxy-5-(trifluoromethyl)-; 5-Trifluoromethyl-6-methoxy-1-naphthonitrile
EINECS	Contact for details

Quality Control

Our 1-Cyano-6-Methoxy-5-(Trifluoromethyl)Naphthalene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. The container should be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.